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  • By responding, N-benzoyl-3-(B-carboxyethyl)- dihydroindole (see JCS, 3158 (1931) for the planning of this compound) with thionyl chloride, trailed by aluminum chloride gives 1-benzoyl-5-keto-1,2,2a,3,4,5-hexahydrobenzindole.
  • This is then brominated to give the 4-Bromo-subordinate, which is changed over to the ketol-ketone by responding with methylamine CH3)2CO ethylene ketol.
  • Acetylate and decrease this ketone with sodium borohydride to get the alcohol, which is changed over to the hydrochloride structure, not surprisingly.

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